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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2018 March;177(3):72-8

DOI: 10.23736/S0393-3660.17.03491-X

Copyright © 2017 EDIZIONI MINERVA MEDICA

lingua: Inglese

Beneficial effect of hyperbaric oxygenation in avascular necrosis of the femoral head

Giuliano VEZZANI 1, Enrico M. CAMPORESI 2, Devanand MANGAR 2, Thomas BERNASEK 3, Zhongjin YANG 4, Silvia QUARTESAN 1, Alex RIZZATO 1 , Gerardo BOSCO 1

1 Department of Biomedical Sciences, University of Padua, Padua, Italy; 2 Department of Anesthesia, Tampa General Hospital, Tampa, FL, USA; 3 Florida Orthopedic Institute, Tampa, FL, USA; 4 The Institute for Human Performance, SUNY Upstate Medical University, Syracuse, NY, USA


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BACKGROUND: Avascular necrosis of the femoral head (ANFH) is a progressive and debilitating disease which eventually requires hip joint surgery. In this retrospective study, we evaluated the efficacy of hyperbaric oxygen treatment (HBO) in ANFH patients (FICAT I-II-III) for four consecutive years.
METHODS: 217 patients with ANFH, enrolled from 2004 to 2013, were included. They received 90 HBO sessions over 12 months. Magnetic resonance imaging (MRI) was obtained prior to treatment and after 12 months. Visual Analogue Scale (VAS) pain scores Femoral head survival were also evaluated at a 4-years follow-up.
RESULTS: Obtained data show that HBO significantly alleviated joint pain and improved joint structure in patients at all stages even if best results were obtained at stage I-II. Improvements remain substantially unchanged for about 4 years. Hip surgery was not necessary in most of the patients with stage I and II and in almost half the patients with stage III.
CONCLUSIONS: HBO appears to be a viable treatment modality in patients with Ficat I, II, even III ANFH.


KEY WORDS: Femur head necrosis - Hyperbaric oxygenation - Magnetic resonance imaging - Visual Analog Scale

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