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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

Rivista di Medicina Interna e Farmacologia


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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2017 November;176(11):610-2

DOI: 10.23736/S0393-3660.16.03428-8

Copyright © 2016 EDIZIONI MINERVA MEDICA

lingua: Inglese

The correlation between serum level of pro b-type natriuretic peptide and severity of mitral valve stenosis as well as other related cardiac hemodynamic parameters

Afsoon FAZLINEZHAD 1, Zahra REZAEI YAZDI 2, Fatemeh ALIZADEH SANI 3, Azra IZANLOO 4

1 Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; 2 Rheumatic Disease Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; 3 Razavi Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad, Iran; 4 Research and Education Department, Razavi Hospital, Mashhad, Iran


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BACKGROUND: As we know, prognosis and severity of mitral valve disease are reflected in their NT-Pro-BNP. Therefore, in this study, we decided to investigate the relationship between severity of mitral valve stenosis and a number of cardiac hemodynamic parameters in order to use this marker with great certainty for diagnosis and prognosis of the patients with mitral valve problems.
METHODS: This study is a correlational study in which all patients with rheumatismal stenosis of mitral valve underwent echocardiography using last AHA/ASE guidelines and pro-Bnp assay regardless of their age. Then the data were analyzed statistically.
RESULTS: A total number of 61 patients with the mean age 46.7±12.37 (29.5% male) were included in the study. Finding showed no significant difference between Pro-BNP and MS (P=0.054), MR (P=0.775) and FC (P=0.217).
CONCLUSIONS: The results showed that Pro-BNP can be used as a factor to predict the diagnosis and prognosis of the patients, but further studies are recommended.


KEY WORDS: Pro-brain natriuretic peptide - Echocardiography - Mitral valve stenosis

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Publication History

Issue published online: September 30, 2017
Manuscript accepted: October 21, 2016
Manuscript received: October 8, 2016

Per citare questo articolo

Fazlinezhad A, Rezaei Yazdi Z, Alizadeh Sani F, Izanloo A. The correlation between serum level of pro b-type natriuretic peptide and severity of mitral valve stenosis as well as other related cardiac hemodynamic parameters. Gazz Med Ital - Arch Sci Med 2017;176:610-2. DOI: 10.23736/S0393-3660.16.03428-8

Corresponding author e-mail

a.izanloo@yahoo.com