Minerva Gastroenterology 2021 Apr 16

DOI: 10.23736/S2724-5985.21.02850-3

Copyright © 2021 EDIZIONI MINERVA MEDICA

lingua: Inglese

Robotic versus laparoscopic total mesorectal excision for rectal cancer: a meta-analysis of long-term survival and urogenital functional outcomes

Xian LI ¹, Zhen-Hua LIU ², Ning WANG ³, Jie DING ¹ ✉, Fei FAN ¹, Xiang-Ying CEN ⁴, Ming WU ⁵, Rui MI ⁶, Hang LIU ⁷, Yuan-Ling ZHANG ⁸

¹ Department of Gastrointestinal Surgery, Guizhou Provincial People’s Hospital, Guiyang, China; ² Department of Pharmacy, Guizhou Orthopedic Hospital, Guiyang, China; ³ Department of Hepatobiliary Surgery, Guizhou Provincial People’s Hospital, Guiyang, China; ⁴ Graduate School of Zunyi Medical University, ZunYi, China; ⁵ Department of Emergency Medicine, Guizhou Provincial People’s Hospital, Guiyang, China; ⁶ Department of Gastrointestinal Surgery, Zhijin county People’s Hospital, Bijie, China; ⁷ Department of Integrated Surgery, Chongqing General Hospital, Chongqing, China; ⁸ Guizhou University Medical College, Guiyang, China

OBJECTIVE: Robotic surgical technology has been widely introduced and applied in various fields of surgery. The aim of this study was to analyze long-term oncological and urogenital functional outcomes following laparoscopic/robotic total mesorectal excision (TME) in rectal cancer surgery.
MATERIALS AND METHODS: We identified studies that compared oncological and functional outcomes following laparoscopic TME (LTME) and robotic TME (RTME) for treatment of rectal cancer over the past 16 years. Data related to overall survival (OS), disease-free survival (DFS), International Prostate Symptom Score (IPSS), and International Index of Erectile Function (IIEF) were subjected to meta-analysis.
RESULTS: There was no difference in long-term OS and DFS in the pooled data. Compared with LTME, there were significant differences in the score of IPSS at 3, 6 and 12 months for RTME, in the pooled data for male patients. There were significant differences in IIEF score for male patients at 3 and 6 months.
CONCLUSIONS: Compared with LTME, RTME has better preservation of urinary and sexual functions and comparable long-term oncological outcome in rectal cancer.

KEY WORDS: Rectal cancer; Robotic surgery; Laparoscopic surgery; Total mesorectal excision; Meta-analysis