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European Journal of Physical and Rehabilitation Medicine 2021 Sep 20

DOI: 10.23736/S1973-9087.21.06663-6

Copyright © 2021 EDIZIONI MINERVA MEDICA

lingua: Inglese

Unusual sensory-motor neuropathies in post Covid-19 patients admitted in rehabilitation hospitals: a case-series

Eliana BERRA , Cira FUNDARÒ, Pierluigi CHIMENTO, Michelangelo BUONOCORE

Clinical Neurophysiology Unit, Istituti Clinici Scientifici Maugeri IRCCS of Pavia and Montescano, Pavia, Italy


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BACKGROUND: Several neurological complications occurred in SARS-Cov2-Disease (COVID-19), mainly related to inflammatory and vascular disorders. The involvement of the Peripheral Nervous System (PNS) has been mostly reported as Guillain-Barrè syndrome, while focal peripheral neuropathies have been rarely described.
CASE SERIES: We report the cases of ten patients hospitalized in Rehabilitation Units after COVID-19, who presented severe focal motor involvement. Electrophysiological investigations revealed focal sensory-motor neuropathies, atypical for many aspects: bilaterality, location and contemporary involvement of different nervous districts. We speculate that their pathogenesis is possibly related to prolonged abnormal postures maintained during hospitalization in Intensive Care Unit, virus neurotropism and thrombotic vascular damage involving vasa nervorum.
CLINICAL REHABILITATION IMPACT: Motor neuropathies could induce severe disability and their early recognition in post COVID-19 patients is of primary importance for a specific rehabilitation treatment.


KEY WORDS: Neuropathies; Peripheral nervous system; COVID-19; Case series; Neurorehabilitation

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