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Europa Medicophysica 2007 June;43(2):147-53


lingua: Inglese

Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension: short-term functional assessment in a longitudinal study

Petrucci L. 1, Carlisi E. 2, Ricotti S. 1, Klersy C. 3, D’Armini A. M. 4, Viganò M. 4, Dalla Toffola E. 5

1 Department of Rehabilitation IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy 2 School of Specialization in Physical Medicine and Rehabilitation, University of Pavia, Pavia, Italy 3 Department of Clinical Biometrics and Epidemiology IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy 4 Unit of Cardiac Surgery University of Pavia, Pavia, Italy 5 Unit of Physical Medicine and Rehabilitation University of Pavia, Pavia, Italy


Aim. Presently, the surgical treatment choice in chronic thromboembolic pulmonary hypertension (CTEPH) consists in a pulmonary endarterectomy (PEA). The aim of the present study is the functional assessment of patients submitted to PEA both preoperatively and shortly after the intervention. A longitudinal study was developed to study the quality and quantity of functional performance possible in these subjects.
Methods. Twenty-two subjects were assessed immediately prior to PEA and 3 months later in order to obtain quantitative measurements of short-term functional recovery. The functional assessment included the 6-min walk test (6mWT), the measurement of the oxygen percent saturation (HbS%O2) and the degree of dyspnea subjectively perceived by each patient.
Results. Three months after the surgical intervention, there was a definite increase in the number of meters walked during the 6mWT with respect to preintervention; the difference between the distances walked in the 6mWT (6mWD) in the pre and post-PEA was statistically significant (Paired t-test P<0.001).
Conclusion. In this study the 6mWT resulted to be a useful tool in the functional evaluation of patients affected by CTEPH and submitted to PEA. The average 6mWD significantly improved already at 3 months after the intervention, thus reaching the minimum limit of the range predicted for the healthy control, but remains lower than the average theoretical value predicted (about 75% of the same).

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