ORIGINAL ARTICLE   Open access

Italian Journal of Emergency Medicine 2020 December;9(3):169-77

DOI: 10.23736/S2532-1285.20.00039-7

Copyright © 2020 THE AUTHORS

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lingua: Inglese

The predictive value of qSOFA and CURB-65 scores in predicting the hospitalization need and mortality in patients with acute exacerbation of chronic obstructive pulmonary disease

Şenol ARSLAN ¹ ✉, Orhan DELICE ¹, Zeynep YEGIN KATRAN ²

¹ Department of Emergency Medicine, Erzurum Regional Training and Research Hospital, Erzurum, Turkey; ² Department of Respiratory Medicine, Erzurum Regional Training and Research Hospital, Erzurum, Turkey

BACKGROUND: Chronic obstructive pulmonary disease (COPD), which is characterized by progressive airway obstruction and recurrent acute exacerbations due to the inflammatory response. COPD is related to high morbidity, mortality rates, and high healthcare costs. Our study aimed to evaluate the predictive value of qSOFA and CURB-65 scores in determining the hospitalization, duration of hospital stay, ICU or inpatient clinic stay, and mortality in COPD patients with acute exacerbation.
METHODS: Our study was designed as a definitive cross-sectional prospective research. COPD patients who applied to the hospital with acute exacerbation between March 2019-September 2019 were included in the study. For each patient, the study form, which included blood sample test results, demographic data, and vital findings, were filled.
RESULTS: No statistically significant difference was detected between patients who were hospitalized in the ICU and the inpatients’ clinics regarding the CURB-65 scores. However, qSOFA score≥2 and qSOFA score being 3 were related to ICU hospitalization. There was a statistically significant relationship between CURB-65≥2 and qSOFA scores and hospitalization status. Among all the patients, there was a statistically significant relationship between mortality and CURB-65 and qSOFA≥2 scores. Statistical analyses showed that the specificity of qSOFA in predicting 28-days mortality was higher than CURB-65. However, CURB-65 had a higher sensitivity. When CURB-65≥2 and qSOFA≥2 were combined, the sensitivity and specificity values were found to be 100% and 60%, respectively.
CONCLUSIONS: qSOFA and CURB-65 scoring systems revealed to be useful in predicting mortality in acute exacerbation of COPD.

KEY WORDS: Lung diseases; Mortality; Symptom Flare Up; Pulmonary disease, chronic obstructive