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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

Rivista di Dermatologia e Malattie Sessualmente Trasmesse


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2018 Jan 24

DOI: 10.23736/S0392-0488.18.05872-8

Copyright © 2018 EDIZIONI MINERVA MEDICA

lingua: Inglese

Skin manifestations of rheumatoid arthritis

Viviana LORA 1, Lorenzo CERRONI 2, Carlo COTA 3

1 Division of Dermatology, San Gallicano Dermatological Institute, Rome, Italy; 2 Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria


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Rheumatoid arthritis is a chronic systemic disease that, in addition to articular involvement, may exhibit a variety of extraarticular manifestations. The skin is frequently involved mainly in the most severe forms of the disease. Rheumatoid nodules, accelerated rheumatoid nodulosis, rheumatoid nodulosis, Felty syndrome, rheumatoid vasculitis, pyoderma gangrenosum, rheumatoid neutrophilic dermatosis, interstitial granulomatous dermatitis, and palisaded neutrophilic granulomatous dermatitis are reviewed both clinically and histologically. Moreover, cutaneous reactions related to treatments of rheumatoid arthritis, in particular to biologic agents, are described. Early recognition of these entities through a clinical and histological correlation permit to optimize the management of patients.


KEY WORDS: Rheumatoid arthritis - Skin - Rheumatoid nodules - Interstitial granulomatous dermatitis - Palisaded neutrophilic granulomatous dermatitis - Biological drug

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Publication History

Article first published online: January 24, 2018
Manuscript accepted: January 4, 2018
Manuscript received: November 29, 2017

Per citare questo articolo

Lora V, Cerroni L, Cota C. Skin manifestations of rheumatoid arthritis. G Ital Dermatol Venereol 2018 Jan 24. DOI: 10.23736/S0392-0488.18.05872-8

Corresponding author e-mail

carlocota@yahoo.it