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Chirurgia 2017 April;30(2):37-9

DOI: 10.23736/S0394-9508.16.04595-2

Copyright © 2016 EDIZIONI MINERVA MEDICA

lingua: Inglese

Evaluation of a dietary supplement in the treatment of cyclical mastalgia

Chiara ROGANTINI 1, Elena SANTORI 1, Giorgio M. BARATELLI 2

1 Accademia di Senologia, Gravedona ed Uniti, Como, Italia; 2 Ospedale di Gravedona, Gravedona ed Uniti, Como, Italia


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BACKGROUND: Cyclical mastalgia is a common symptom experienced by women of reproductive age; many etiopathogenetic hypothesis have been formulated, and many treatments have been proposed. We tested an anti-inflammatory and anti-edematous dietary supplement, to treat patients with moderate and severe cyclical mastalgia.
METHODS: From June, 2014 to April, 2015, a dietary supplement with anti-inflammatory and anti-edematous properties (Deflogo SD®) was administered to 50 women, 32 with moderate cyclical mastalgia, aged 20-52 (mean age 37), and 18 with severe cyclical mastalgia, aged 28-53 (mean age 42). The study was conducted at the Breast Center of “Delegazione dell’Alto Lario”, of the Lega Italiana per la Lotta contro i Tumori (LILT) of Gravedona (Italy). The weight, height, bra-size, clinical history (number of pregnancies, extent of breast-feeding, usage of oral contraceptives), personal habits (consumption of coffee, physical activity), and breast density of the patients were recorded.
RESULTS: Twelve women dropped out; 38 of 50 patients were evaluated, 26 with moderate and 12 with severe breast pain. The overall response (gathering the cases of reduction with the ones of pain resolution) has been 92.1 %. Women with moderate cyclic breast pain have generally responded better than women with intense cyclic breast pain (96.1% vs.83.3%). Mild collateral effects were observed in 8% of women.
CONCLUSIONS: Our results show that the dietary supplement (Deflogo SD®) is effective and safe to treat patients with moderate or intense cyclical mastalgia.


KEY WORDS: Mastodynia - Breast diseases - Anti-inflammatory agents

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Publication History

Issue published online: January 27, 2017
Manuscript accepted: October 13, 2016
Manuscript received: February 25, 2016

Per citare questo articolo

Rogantini C, Santori E, Baratelli GM. Evaluation of a dietary supplement in the treatment of cyclical mastalgia. Chirurgia 2017;30:37-9. DOI: 10.23736/S0394-9508.16.04595-2

Corresponding author e-mail

chiara.rogantini01@universitadipavia.it