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Italian Journal of Maxillofacial Surgery 2008 December;19(3):131-6


lingua: Inglese

Adenomatoid odontogenic tumor: review of the literature and clinical series

Spotti S. 1, Valsecchi S. 1, Ardito E. 3, Pilatti A. 2, Gervasoni C. 1

1 Maxillo-Facial Surgery Department S. Anna Hospital, Como, Italy 2 Patologic Anatomy Service Department of Diagnosis and Cure S. Anna Hospital, Como, Italy 3 Maxillo-Facial School of Medicine University of Milan Bicocca, Monza, Italy


Authors have analyzed the last 30 years of international literature and present hereby two cases of a rare neoplasm of the maxillary bones: the adenomatoid odontogenic tumor (AOT). This neoplasm is an amartomatous, non-invasive lesion with slow but progressive growing. AOT represents the 3% of all odontogenic tumors. AOT had been initially described and classified as a variant of the ameloblastoma and has been recognized as a distinct lesion only since 1990. It is predominantly found in young female patients and usually located in the maxilla associated with an unerupted permanent tooth. This article describes two cases concerning two young female patients who presented at our Department in the period comprised between December 2006 and February 2008 with an asymptomatic swelling with a slowly growing lesion: a 29-year-old patient with a lesion in the maxilla associated with unerupted left canine and a 17-year-old girl presenting AOT with unerupted right canine in the anterior mandible. Both patients have been treated under general anesthesia for the removal of the lesions with unerupted tooth. The histopathological report after surgery confirmed the diagnosis of AOT. The postoperative course and follow-up were uneventful. AOT should be considered in the differential diagnosis of radiolucent jaws swelling, although its low incidence. The surgical treatment of such neoplasm is generally conservative, provided that the removal of the lesion and the curettage of the residual area are meticulously performed; in these conditions recurrence is extremely rare.

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