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The Journal of Cardiovascular Surgery 2018 Feb 08

DOI: 10.23736/S0021-9509.18.10132-7

Copyright © 2018 EDIZIONI MINERVA MEDICA

lingua: Inglese

Abdominal aortic aneurysm calcification: trying to identify a reliable semiquantitative method

Marina DIAS-NETO 1, 2 , Emmanuel NEVES 2, Fábio SOUSA-NUNES 3, Tiago HENRIQUES-COELHO 2, 4, Sérgio SAMPAIO 1, 5

1 Department of Angiology and Vascular Surgery, São João Hospital Centre, Porto, Portugal; 2 Cardiovascular Research Centre, Faculty of Medicine, University of Porto, Porto, Portugal; 3 Faculty of Medicine, University of Porto, Porto, Portugal; 4 Department of Pediatric Surgery, São João Hospital Centre, Porto, Portugal; 5 Centre for Research in Health Technologies and Information Systems and Department of Community Medicine, Information and Health Decision, Faculty of Medicine, University of Porto, Porto, Portugal


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BACKGROUND: The main objective of this study was to assess the correlation between three semiquantitative and one computerized method based on Agatston Score (AS), when measuring abdominal aortic calcification (AAC) in abdominal aortic aneurysm (AAA) patients. Secondary aim was to access differences in AAC upon clinical variables, when different methods of calcium scoring are used.
METHODS: This was an observational, retrospective, cross-sectional study. A database of AAA patients consecutively submitted to elective repair between 2008 and 2015 was used. Patients were excluded if they did not have preoperative imaging or presented scans incompatible with at least one of the whole set of calcification methods tested. Calcification measures were performed using AS, aortic calcification index (ACI), AAC-8 and AAC-24 methods. The Pearson’s correlation was used for primary analysis.
RESULTS: Study population comprised 102 patients, 95% males, with a median age of 71 (interquartile range, IQR 66-76) years. AAAs presented median aortic diameter of 60 (54- 70) mm. Pearson’s correlation with AS was 0.816 for ACI, 0.703 for AAC-8 and 0.648 for AAC-24. ACI also presented the highest ICC for intraobserver agreement (0.972) and for interobserver agreement (0.966). ACI was associated more often to demographic and clinical variables in the dataset that associated with the computerized method.
CONCLUSIONS: ACI is suggested as a fast and easy-to-use method of assessing AAC in AAA patients. Its use should be encouraged to study AAC in AAA over other semiquantitative methods, in research settings.


KEY WORDS: Abdominal aortic aneurysm - Vascular calcification - Computed tomography - Observational study

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