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The Journal of Cardiovascular Surgery 2013 August;54(4):441-5

Copyright © 2013 EDIZIONI MINERVA MEDICA

lingua: Inglese

Nitinol stents with polymer-free paclitaxel coating for stenosis of failing infrainguinal bypass grafts

Airoldi F. 1, Baldino G. 2, Mortola P. 2, Losa S. 1, Clerici G. 1, Tavano D. 1, Latib A. 3, Gori A. 2, Faglia E. 1

1 Cardiovascular Department, Multimedica IRCCS, Sesto San Giovanni, Milan, Italy; 2 Vascular Surgery Unit, Galliera Hospital, Genoa, Italy; 3 Division of Cardiology, University of Cape Town, Cape Town, South Africa


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Aim: This study was designed to investigate the immediate and one-year outcomes of polymer-free paclitaxel coated drug-eluting stent (DES) implantation in a consecutive series of patients presenting with stenosis of infrainguinal bypass grafts.
Methods: Between January 2011 and January 2012, 11 patients with failing infrainguinal bypass grafts were treated in two institutions. Clinical status and Duplex scan parameters were recorded at baseline and over a follow-up period of one year.
Results: DES implantation was successfully performed in all patients. Ten patients received a single stent and one patient received two stents. At one year, one patient showed total bypass graft occlusion (9%). In all the remaining patients, Duplex scan examination documented patency of the treated grafts.
Conclusion: DES implantation in failing infrainguinal bypass grafts can be safely performed and provides satisfactory clinical outcomes. The patency rate of 91% favourably compares with those obtained with other endovascular treatments such as plain balloon or cutting balloon angioplasty.

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