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  INNOVATIVE TECHNOLOGIES FOR SUPERFICIAL FEMORAL ARTERY (SFA) OCCLUSIONS 

The Journal of Cardiovascular Surgery 2012 August;53(4):481-6

Copyright © 2012 EDIZIONI MINERVA MEDICA

lingua: Inglese

Innovative technologies for SFA occlusions: drug coated balloons in SFA lesions

Minar E., Schillinger M.

Medical University of Vienna, Angiology Medical University, Vienna, Austria


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The concept of using a balloon catheter to directly deliver an antiproliferative drug at the site of injury has become one of the most interesting technological developments in endovascular therapy. There have been important advances in knowledge concerning balloon-based drug delivery technologies during the last years, and different methods have been developed by different companies to coat the balloon with the antiproliferative agent. Currently there is a rapidly increasing clinical study program using drug coated balloons (DCB) in different locations and indications. There are four already finished randomized studies in patients with superficial femoral artery lesions investigating the efficacy of paclitaxel release by DCB, and all demonstrated significantly improved patency rates compared to balloon angioplasty with non coated balloons. DCB offer several advantages compared to drug eluting stents, since any stentless technology for improvement of longterm patency is preferable to overcome the drawbacks of stenting. This technology has demonstrated the capacity to have a significant impact on the practice of percutaneous cardiovascular interventions in the future.

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