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ORIGINAL ARTICLES  LOWER LIMB ISCHEMIA 

The Journal of Cardiovascular Surgery 2008 April;49(2):145-9

Copyright © 2008 EDIZIONI MINERVA MEDICA

lingua: Inglese

Heparin-bonded expanded polytetrafluoroethylene grafts for infragenicular bypass in patients with critical limb ischemia: 2-year results

Dorrucci V., Griselli F., Petralia G., Spinamano L., Adornetto R.

Department of Vascular Surgery Umberto I Hospital, Venice, Italy


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Aim. The use of prosthetic grafts in below-knee (BK) bypasses may be necessary in patients with no available autologous vein and critical limb ischemia not amenable to angioplasty. Such conduits, however, have generally yielded disappointing results.
Methods. A new heparin-bonded expanded polytetrafluoroethylene graft (Gore-Tex Propaten Vascular Graft) designed to provide resistance to thrombosis may be associated with decreased early graft failure and increased patency. This graft was implanted in 27 limbs (26 patients; 18 men; mean age 71 years; Rutherford class 4 to 6 disease) in a BK femoropopliteal and femorodistal location, without perioperative complications and with immediate graft patency.
Results. During a mean follow-up time of 24 months, 4 cases of thrombosis occurred, all at least 6 months postoperatively: 2 cases resolved after fibrinolytic treatment, 1 required surgical revision and in 1 case, amputation was required because of a delay in seeking treatment for thrombosis. Two patients died of cardiac disease during follow-up. The 2-year primary and secondary patency rates for the BK bypasses were 85% and 93%, respectively; the limb-salvage rate was 96%.
Conclusion. These results are encouraging for a prosthetic graft, especially in the light of the severity of the vascular disease in the limbs treated.

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