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The journal of Cardiovascular Surgery 2004 December;45(6):569-71

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

Recombinant factor VIIa use in cardiac surgery - expanding the arsenal therapy for intractable bleeding?

Kogan A. 1, Berman M. 1, Stein M. 2, Vidne B. A. 1, Raanani E. 1

1 Department of Cardiothoracic Surgery Rabin Medical Center, Beilinson Campus Petach Tikva, Israel 2 Trauma Unit Rabin Medical Center, Beilinson Campus Petach Tikva, Israel


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A 72-year-old patient was admitted for mitral valve replacement because of infective endocarditis. Severe intractable bleeding in the early postoperative period was successfully treated with recombinant activated factor VII (rFVIIa). Thereafter, recovery was uneventful, and the patient was discharged on postoperative day 16. The current clinical aspects and experience of rFVIIa use in cardiac surgery are discussed.

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