Home > Riviste > The Journal of Cardiovascular Surgery > Fascicoli precedenti > The Journal of Cardiovascular Surgery 2002 October;43(5) > The Journal of Cardiovascular Surgery 2002 October;43(5):723-7

ULTIMO FASCICOLO
 

JOURNAL TOOLS

eTOC
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca
 

ARTICLE TOOLS

Estratti
Permessi

 

ORIGINAL ARTICLES  THORACIC SECTION 

The Journal of Cardiovascular Surgery 2002 October;43(5):723-7

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

Surgical treatment of stage I lung cancer. Results and prognostic factors

Porrello C., Alifano M., Forti Parri S. N., Sanna S., Lacava N., Corneli G., Boaron M.

Department of Thoracic Surgery Maggiore Hospital, Bologna, Italy


PDF


Back­ground. The ­aims of the ­present ­study ­were: 1) to ­study the ­type and ­extent of resec­tion in ­patients ­with path­o­log­ical ­stage I ­lung ­cancer; 2) to eval­uate the ­results of sur­gical treat­ment; 3) to ­assess prog­nostic fac­tors. Set­ting: a ter­tiary ­referral gen­eral hos­pital.
­Methods. Ret­ro­spec­tive ­review of clin­ical ­records of 296 ­patients oper­ated on for path­o­logic ­stage I ­lung ­cancer ­between 1989 and 1998. ­Mean ­follow-up ­period was 33.1±28.1 ­months. Sur­vi­vals ­were cal­cu­lated by the actu­arial ­method and com­pared by the ­long-­rank ­test. Age, sex, ­tumor ­size, ­type and ­extent of resec­tion and his­to­logic ­type ­were eval­u­ated by uni­var­iate and mul­ti­var­iate anal­isis.
­Results. Two hundred and forty-five lobec­to­mies, 39 pneu­mo­nec­to­mies, 5 seg­mental resec­tions and 7 ­wedge resec­tions ­were per­formed. ­Overall actu­arial 5-­ and 10-­year sur­vi­vals ­were 62 and 49%, respec­tively. ­Stage Ia ­patients ­showed sig­nif­i­cantly ­better 5- and 10-­year sur­vi­vals (76 and 54%, respec­tively) as com­pared to ­Stage Ib ­patients (57 and 46%, p=0.007). Uni­var­iate anal­ysis ­showed no sig­nif­i­cant dif­fer­ence in sur­vival ­according to the age, the sex or the ­extent of resec­tion. The his­to­log­ical ­type influ­enced the out­come (p=0.05): 5-­year sur­vival ­rate ­were 57, 67, 75% in squa­mous ­cell car­ci­noma, adenocarcinoma and bron­choal­ve­olar car­ci­noma, respec­tively. At mul­ti­var­iate anal­ysis ­stage and his­tology ­were iden­ti­fied as inde­pen­dent prog­nostic fac­tors.
Con­clu­sions. Sat­is­fac­tory ­results in ­terms of ­suvival can be ­achieved fol­lowing sur­gery for ­stage I ­lung ­cancer. The T ­status and the his­to­logic ­type sig­nif­i­cantly influence sur­vival.

inizio pagina