ORIGINAL ARTICLE   

Otorhinolaryngology 2021 December;71(4):255-9

DOI: 10.23736/S2724-6302.21.02354-9

Copyright © 2021 EDIZIONI MINERVA MEDICA

lingua: Inglese

Mean platelet volume and red blood cell distribution width as a bleeding predictor in post-tonsillectomy hemorrhage

Ergun SEVIL ¹ ✉, Fatih YUCEDAG ², Ismail CEVIK ²

¹ Department of Otorhinolaryngology Head and Neck Surgery, Trabzon Kanuni Training and Research Hospital, Trabzon, Turkey; ² Department of Otorhinolaryngology Head and Neck Surgery, Karaman Training and Research Hospital, Karaman, Turkey

BACKGROUND: Red cell distribution width (RDW), a well-known indicator for inflammation, indicates the variability of the size of the red blood cells in circulation and mean platelet volume (MPV) is the most used measure of platelet size, and is an essential indicator of platelet function and activation.
METHODS: The study included 50 patients who suffered post tonsillectomy bleeding (Group 1, Group 2) and a control group (Group 3) of 48 subjects with no post-tonsillectomy bleeding. The patients with post-tonsillectomy bleeding were separated into 2 subgroups as Group 1 with bleeding determined 1-7 days postoperatively, and Group 2, as those with the onset of bleeding at seven days or later. MPV and RDW parameters were examined and compared between the two groups.
RESULTS: Mean RDW was 13.14 in the bleeding group and 13.58 in the control group. Mean MPV was 9.6 in the bleeding group and 10 in the control group. The results of analysis of the three groups showed no significant difference between the groups in terms of RDW and MPV (P>0.05). The average RDW ranged between 12.93 in Group 2 and 13.58 in Group 3. MPV had a range between 9.61 in Group 1 and 10.07 in Group 3. Spearman’s correlation analysis was applied to RDW against the difference between preoperative and postoperative hematocrit and hemoglobin values, and no significant relationship was determined between the studied variables (P<0.05).
CONCLUSIONS: This study has shown a clinical finding of lower preoperative MPV and RDW values in patients with postoperative tonsillectomy bleeding.

KEY WORDS: Mean platelet volume; Erythrocytes; Tonsillectomy; Hemorrhage