Home > Riviste > Otorhinolaryngology > Fascicoli precedenti > Otorhinolaryngology 2021 September;71(3) > Otorhinolaryngology 2021 September;71(3):249-53



Opzioni di pubblicazione
Per abbonarsi
Sottometti un articolo
Segnala alla tua biblioteca


Publication history
Per citare questo articolo



Otorhinolaryngology 2021 September;71(3):249-53

DOI: 10.23736/S2724-6302.20.02302-4


lingua: Inglese

Lichenoid and granulomatous stomatitis of the upper labial mucosa

Gillian WHITE 1, Brendan CONN 2, Thomas P. HANDLEY 1, Rodolfo BENECH 1

1 Department of Oral and Maxillofacial Surgery, St John’s Hospital, Edinburgh, UK; 2 Unit of Oral and Maxillofacial Pathology, Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK

Concomitant lichenoid and granulomatous stomatitis of the oral cavity is a rare entity. It was first described in 2006 with a series of six patients with upper labial mucosa lesions with no dysplasia history. Since then, sixty-three cases of oral lichenoid and granulomatous stomatitis have been reported. We describe a retrospective clinico-pathological study of three cases of lichenoid and granulomatous stomatitis of which, two patients had previous oral squamous cell carcinoma which has not yet been described. All three cases presented with upper labial mucosal lichenoid and granulomatous histopathology. Case one is an 81-year-old male with a previous upper lip squamous cell carcinoma and lower lip carcinoma in situ which was surgically excised in 2011. Case two is a 51-year-old male who previously underwent surgical excision and left selective neck dissection for left buccal mucosa squamous cell carcinoma in 2010. Finally, a 35-year female presented with a non-healing painful upper labial mucosal lesion, managed with regular analgesia and prednisolone tablet mouthwash four times daily with symptom resolution but persisting lesion. We discuss their relevant case background in more detail in context with current literature. The pathogenesis of this rare clinical and histopathological presentation of both lichenoid and granulomatous inflammation remains unclear. Future publication of similar cases detailing responsiveness to any treatments and follow-up is required to better explore its possible relationship with previous malignancy and appropriate management of oral lichenoid and granulomatous stomatitis.

KEY WORDS: Stomatitis; Lichenoid eruptions; Mouth mucosa

inizio pagina