CASE REPORT   

Otorhinolaryngology 2021 March;71(1):35-9

DOI: 10.23736/S2724-6302.20.02290-0

Copyright © 2020 EDIZIONI MINERVA MEDICA

lingua: Inglese

Extramedullary type of solitary nasopharyngeal plasmacytoma: case report and short review of the literature

Ignazio LA MANTIA, Antonino MANIACI ✉, Vittoria BANNÒ, Federica CIPOLLA, Martina RAGUSA, Salvatore COCUZZA

G. F. Ingrassia Department of Medical, Surgical and Advanced Technologies, ENT Section, University of Catania, Catania, Italy

According to the World Health Organization, extramedullary plasmacytoma is a rare myelomatous variant, which represents about 3% of solitary plasmacytoma characterized by extra-bone diffusion and serum agammaglobulinemia. The patient’s medical history and symptoms vary widely depending on the tumour site and the degree of locoregional involvement and spread. Radiation therapy is the standard treatment for extramedullary plasmacytoma (EMP), while surgery should be reserved for the treatment of resection of well-defined masses - but always in combination with the former. We describe the case of a 57-year-old patient with a long-term nasal obstruction and irregular bleeding - which has been diagnosed with EMP of the nasopharynx. The patient was treated with surgery followed by radiation therapy with a satisfactory result, to date negative follow-up for ongoing relapses.

KEY WORDS: Antigens, neoplasm; plasmacytoma; Soft tissue neoplasms; Disease-free survival