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Italian Journal of Dermatology and Venereology 2021 Apr 29

DOI: 10.23736/S2784-8671.21.06645-1


lingua: Inglese

Quality of life, anxiety, depression, social anxiety and avoidance in patients with chronic hand eczema

Serap MADEN 1 , Ozlem OZBAGCIVAN 2, Behice E. ONUR AYSEVENER 3, Sebnem AKTAN 2

1 Department of Dermatology, Faculty of Medicine, Near East University, Nicosia, North Cyprus, Turkey; 2 Department of Dermatology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey; 3 Department of Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey


BACKGROUND: Previous studies have demonstrated that chronic hand eczema (CHE) causes negative effects on psychological status of patients. However, presence of social anxiety and avoidance has not been investigated in CHE patients. In this descriptive and prospective study, we aimed to examine the psychosocial dimensions of CHE in a more detailed manner.
METHODS: 70 patients with CHE and 70 controls were participated in the study. The quality of life (QoL) was assessed with the World Health Organization QoL Questionnaire-Short Form (WHOQoL-BREF); anxiety and depression were evaluated with the Hospital Anxiety and Depression Scale (HADS); and social anxiety and avoidance were evaluated with the Liebowitz Social Anxiety Scale (LSAS).
RESULTS: The physical and environmental subscale scores of the WHOQoL-BREF were significantly lower (P<0.001, P=0.041); whereas HADS-total (P=0.019), HADSanxiety (P=0.014), LSAS-total (P=0.025), LSAS-anxiety (P=0.037) and LSASavoidance (P=0,029) scores were significantly higher in CHE patients compared to controls. The physical (r=-0.260, p=0.002) and social (r=0.204, p=0.016) domains of the WHOQoL-BREF scale negatively correlated with the severity of eczema, while the psychological (r=-0.363, p=0.002) and environmental (r=-0.456, p<0.001) domains negatively correlated with the extent of eczema. HADS-total (r=0.284, p=0.017) and HADS-depression (r=0.311, p=0.009) also showed positive correlations with the extent of the CHE.
CONCLUSIONS: Considering that impairment in QoL may be associated with psychosocial morbidity, it is important to develop strategies to recognize and treat those psychiatric comorbidities in patients with CHE.

KEY WORDS: Contact dermatitis; Depression; Quality of life; Social anxiety disorder

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