SKIN INVOLVEMENT IN CONNECTIVE TISSUE DISEASES 

Giornale Italiano di Dermatologia e Venereologia 2014 October;149(5):549-54

Copyright © 2014 EDIZIONI MINERVA MEDICA

lingua: Inglese

Cutaneous manifestations of lupus erythematosus

Parodi A., Cozzani E. ✉

Di.S.Sal., Section of Dermatology, University of Genoa, IRCCS AOU San Martino-IST Genova, Genoa, Italy

Cutaneous involvement in case of lupus erythematosus (LE) is very frequent and can present both specific or non-specific manifestations. LE specific lesions can be classified in acute, subacute and chronic cutaneous LE lesions. All of them can be localized and generalized. The LE non specific lesions are not exclusive to LE disease but are often seen in patients with active systemic LE. All the cutaneous lesions are often induced or aggravated by ultraviolet light, in fact they are usually localized in sun-exposed areas. Acute cutaneous LE is associated with systemic disease, subacute cutaneous LE has been considered a subset of its own since 1979 when it was first described, chronic cutaneous LE is the most common subtype of LE. Although less frequently also the chronic cutaneous lesions can be an aspect of systemic LE (25%).