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A Journal on Applied Physiology, Biomechanics, Preventive Medicine,
Sports Medicine and Traumatology, Sports Psychology

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The Journal of Sports Medicine and Physical Fitness 2017 Jul 25

DOI: 10.23736/S0022-4707.17.07497-7


language: English

Effects of taurine on markers of muscle damage, inflammatory response and physical performance in triathletes

Bryan S. MARTINEZ GALAN 1, Flavia GIOLO de CARVALHO 1, Priscila CARVALHO SANTOS 1, Ronaldo BUCKEN GOBBI 2, Carlos KALVA-FILHO 3, Marcelo PAPOTI 4, Adelino SANCHEZ SILVA 4, Ellen C. FREITAS 1, 4

1 Postgraduate Program in Food and Nutrition, Faculty of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil; 2 Institute of Biosciences, State University of São Paulo, IB UNESP, Rio Claro, SP, Brazil; 3 Graduate Program in Rehabilitation and Functional Performance, University of São Paulo, FMRP, São Paulo, Brazil; 4 School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil


BACKGROUND: The practice of prolonged exercise with high intensity, as seen in triathlon training, can cause physiological imbalances that might result in muscle fatigue, muscle damage and changes in systemic inflammatory response, thus reduce the athletes physical performance, therefore, both adequate total caloric and macronutrient intake also the use of a specific ergogenic aid, as taurine supplementation would be an alternative to prevent inflammation and muscle damage. In order to verify the effects of 8 weeks of taurine and chocolate milk supplementation, markers of muscle damage, inflammation, and aerobic capacity were quantified in triathletes.
METHODS: A double-blind, crossover, randomized study was conducted with 9 male long distance triathletes, aged 25-35 years. Supplementation of 3 g of taurine (TAU) or placebo (PLA) associated with 400 ml low fat chocolate milk was performed during an 8-week period. In order to verify the effects of the supplementation protocol markers of muscle damage as lactate dehydrogenase (LDH) and creatine kinase (CK), and inflammatory markers tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) were quantified, also triathletes performance was evaluated by exhaust test on a treadmill.
RESULTS: It was observed a significant increase in taurine and CK plasma levels after TAU supplementation (p=0.02 and p=0.01, respectively). However, LDH concentrations did not differ significantly after the supplementations performed, and there were no changes in physical performance parameters; anaerobic threshold, perceived exertion, heart rate, and the concentrations of IL-6 and TNF-α.
CONCLUSIONS: Taurine supplementation did not provide benefits on performance and muscle damage in triathletes.

KEY WORDS: Milk chocolate - Aerobic capacity - Supplementation

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Publication History

Article first published online: July 25, 2017
Manuscript accepted: July 14, 2017
Manuscript revised: June 26, 2017
Manuscript received: February 20, 2017

Cite this article as

Martinez Galan BS, Giolo De Carvalho F, Carvalho Santos P, Bucken Gobbi R, Kalva-Filho C, Papoti M, et al. Effects of taurine on markers of muscle damage, inflammatory response and physical performance in triathletes. J Sports Med Phys Fitness 2017 Jul 25. DOI: 10.23736/S0022-4707.17.07497-7

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