ORIGINAL ARTICLE  EPIDEMIOLOGY AND CLINICAL MEDICINE 

The Journal of Sports Medicine and Physical Fitness 2022 July;62(7):961-8

DOI: 10.23736/S0022-4707.21.12785-9

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Variation in myokine and adipokine levels according to menstrual cycle following regular resistance exercise

Sunghwun KANG ^{1, 2}, Eonho KIM ³, Sungbum JU ⁴, Seung-Taek LIM ⁵ ✉

¹ College of Art, Culture and Engineering, Laboratory of Exercise Physiology, Kangwon National University, Gangwon-do, South Korea; ² Interdisciplinary Program in Biohealth-machinery Convergence Engineering, Kangwon National University, Gangwon-do, South Korea; ³ College of Education, Department of Physical Education, Laboratory of Exercise Physiology, Dongguk University, Seoul, South Korea; ⁴ Department of Physical Education, Busan National University of Education, Busan, South Korea; ⁵ Olympic Studies Center, Kangwon National University, Gangwon-do, South Korea

BACKGROUND: The purpose of this study was to analyze the differences between myokine and adipokine factors under stable conditions according to the menstrual cycle (luteal and follicular phases) and to investigate the effect of regular resistance exercise on the changes in myokine and adipokine factors according to menstrual cycle in obese female college students.
METHODS: The study participants were female college students with a body fat percentage of 30% or more (N.=20), divided into two groups: luteal phase (N.=12) and follicular phase (N.=8). They performed regular resistance exercise three times a week, 60 minutes daily, for 16 weeks. Parameters measured include body composition via impedance, visceral fat area using computed tomography and myokine and adipokine factors in blood.
RESULTS: Levels of BDNF (P<0.05), NGF (P<0.01), and adiponectin (P<0.01) were significantly increased in the luteal phase group after 16 weeks relative to the baseline values. Leptin (P<0.01) was significantly decreased in the luteal phase group after 16 weeks. Weight, Body Mass Index, %fat, and visceral fat area were significantly decreased in both groups after 16 weeks. Muscle mass was significantly increased in both groups after 16 weeks.
CONCLUSIONS: Regular resistance exercise affected the reduction in visceral fat area and had a positive effect on body composition which might be altered favorably by myokines and adipokines. Thus, the timing of blood collection is very important in obese female college students.

KEY WORDS: Menstrual cycle; Resistance training; Exercise; Obesity; Female