Home > Journals > The Journal of Sports Medicine and Physical Fitness > Past Issues > The Journal of Sports Medicine and Physical Fitness 2018 March;58(3) > The Journal of Sports Medicine and Physical Fitness 2018 March;58(3):216-20

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Publication history
Reprints
Permissions
Cite this article as

 

ORIGINAL ARTICLE  EXERCISE PHYSIOLOGY AND BIOMECHANICS 

The Journal of Sports Medicine and Physical Fitness 2018 March;58(3):216-20

DOI: 10.23736/S0022-4707.16.06680-9

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

Acute supplementation of L-arginine affects neither strength performance nor nitric oxide production

Claudia M. MEIRELLES 1 , Cristiane MATSUURA 2

1 School of Physical Education of Army, Rio de Janeiro, Brazil; 2 Department of Pharmacology and Psychobiology, State University of Rio de Janeiro, Rio de Janeiro, Brazil


PDF


BACKGROUND: L-arginine is a semi-essential amino acid involved in nitric oxide production. As nitric oxide is an important vasodilator, L-arginine supplementation would increase blood perfusion and, subsequently, muscle performance during exercises. The aim of this study was to determine the acute effect of L-arginine supplementation on strength performance and nitric oxide levels in healthy trained individuals.
METHODS: In a double-blind, placebo-controlled, cross-over study, 12 men were randomly assigned to L-arginine or placebo supplementation. Subjects received 6 g of L-arginine or placebo 60 minutes before strength test (maximum number of repetitions, 3 sets at 70% of one repetition maximum on bench press and at 80% of one repetition maximum on knee extensions, 2 minutes of rest between sets and exercises). Blood samples were collected before supplementation and 6 min after exercise.
RESULTS: Plasma nitrite levels did not significantly change after L-arginine or placebo supplementation and strength-training exercise (placebo, from 13.01±1.18 to 11.83±2.81 mM; L-arginine, from 10.95±4.09 to 11.99±2.5 mM). There was a significant reduction in the number of repetitions performed from set 1 to set 3 in each set of both bench press and knee extension, but no significant interactions were observed between placebo and L-arginine.
CONCLUSIONS: These results do not support the use of L-arginine as an ergogenic aid for strength performance, at least in context of acute use immediately before resistance exercise performance.


KEY WORDS: Dietary supplements - Athletic performance - Resistance training

top of page