Home > Journals > The Journal of Sports Medicine and Physical Fitness > Past Issues > The Journal of Sports Medicine and Physical Fitness 2000 December;40(4) > The Journal of Sports Medicine and Physical Fitness 2000 December;40(4):336-42

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

ORIGINAL ARTICLES   

The Journal of Sports Medicine and Physical Fitness 2000 December;40(4):336-42

Copyright © 2001 EDIZIONI MINERVA MEDICA

language: English

Acute creatine loading enhances human growth hormone secretion

Schedel J. M. 1, 2, 3, Tanaka H. 2, Kiyonaga A. 2, Shindo M. 2, Schutz Y. 3

1 Laboratory of Exercise Physiology and Biomechanics, Graduate School of Physical Education, Chukyo University, Toyota, Japan; 2 Laboratory of Exercise Physiology, Department of Sport Sciences, Fukuoka University, Fukuoka, Japan; 3 Institute of Physiology, Faculty of Medicine, University of Lausanne, Lausanne, Switzerland


PDF


Background. The main objective of this study was to explore the effect of acute creatine (Cr) ingestion on the secretion of human growth hormone (GH).
Methods. In a comparative cross-sectional study, 6 healthy male subjects ingested in resting conditions a single dose of 20 g creatine (Cr-test) vs a control (c-test). During 6 hours the Cr, creatinine and GH concentrations in blood serum were measured after Cr ingestion (Cr-test).
Results. During the Cr-test, all subjects showed a significant stimulation of GH (p<0.05), but with a large interindividual variability in the GH response: the difference between Cr-test and c-test averaged 83% (SD 45%). For the majority of subjects the maximum GH concentration occurred between 2 hrs and 6 hrs after the acute Cr ingestion.
Conclusions. In resting conditions and at high dosages Cr enhances GH secretion, mimicking the response of strong exercise which also stimulates GH secretion. Acute body weight gain and strength increase observed after Cr supplementation should consider the indirect anabolic property of Cr.

top of page