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REVIEW  HRCT OF THE CHEST IN ILD 

Journal of Radiological Review 2021 June;8(2):99-112

DOI: 10.23736/S2723-9284.21.00129-9

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Fibrotic lung diseases on HRCT: imaging and differential diagnosis

Elisa BARATELLA 1 , Cristina MARROCCHIO 1, Chiara ROMEI 2, Adele VALENTINI 3, Marco BUSSO 4, Roberta POLVEROSI 5, Anna Rita LARICI 6, 7, Maria A. COVA 1

1 Department of Radiology, University of Trieste, Trieste, Italy; 2 Department of Diagnostic Imaging, Diagnostic Radiology 2, University Hospital of Pisa, Pisa, Italy; 3 Department of Radiology, I.R.C.C.S. Polyclinic San Matteo Foundation, Pavia, Italy; 4 Department of Oncology, SCDU Radiodiagnostica, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy; 5 AFFIDEA-IDA, Padua, Italy; 6 Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology - Diagnostic Imaging Area, “A. Gemelli” University Polyclinic Foundation IRCCS, Rome, Italy; 7 Department of Radiological and Hematological Sciences, Section of Radiology, Catholic University of the Sacred Heart of Rome, Rome, Italy



Interstitial lung diseases (ILDs) represent a heterogeneous group of entities, some of them characterized by an excessive deposition of extracellular matrix, in particular collagen, associated with a progressive destruction of the lung parenchyma. Thig group of diseases includes both idiopathic and secondary conditions. Although the underlying causes are different, some fibrotic lung diseases show a similar chronic progressive behavior, independently of the underlying etiology. An accurate diagnosis is mandatory to guide management and treatment of patients with interstitial lung diseases, in particular those with a fibrotic pattern. Imaging, and in particular high-resolution CT, plays a central role, therefore it is fundamental that radiologists become familiar with these diseases and their presentations, in order to be able to provide one or a limited number of possible differential diagnosis.


KEY WORDS: Pulmonary fibrosis; Tomography, X-ray computed; Lung diseases; Diagnosis, differential

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