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Journal of Radiological Review 2020 November-December;7(6):480-7

DOI: 10.23736/S2723-9284.20.00076-3

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English, Italian

Pleomorphic xanthoastrocytoma of the pineal gland: the seventh case documented, radiological and histological features

Giulia PILLONI 1 , Francesca BOZZETTI 2, Ermanno GIOMBELLI 1, Elena V. COLOMBO 1, Girolamo CRISI 2, Pellegrino CRAFA 3, Letizia GNETTI 3, Fulvio TARTARA 1

1 Department of Neurosurgery, University Hospital of Parma, Parma, Italy; 2 Unit of Neuroradiology, Department of Diagnostic Imaging, University Hospital of Parma, Parma, Italy; 3 Unit of Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy


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Pineal region tumors are rare, with a reported incidence of about 1% of all intracranial neoplasms. Less than 10 cases are reported in literature on pleomorphic xanthoastrocytoma (PXA) of the pineal gland. We report a case of a pineal tumor with pleomorphic aspects at histology. A 68-year-old woman presented with a lesion of the pineal gland with tendency to increase in size after 3 years from the first performed magnetic resonance imaging. Total resection was performed and histological examination confirmed the diagnosis of PXA. Total excision of the lesion represents the first option of treatment for this rare lesion. Histology is fundamental to decide the correct management.


KEY WORDS: Neoplasms; Pineal gland; Astrocytes

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