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Journal of Radiological Review 2020 September-October;7(5):346-56

DOI: 10.23736/S2723-9284.20.00017-2

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English, Italian

Role of multiparametric magnetic resonance imaging in the management of patients with Crohn’s disease

Martina MENNELLA , Maria P. BELFIORE, Roberta GRASSI, Roberta RELLA, Giovanna VACCA, Maria P. ROCCO, Teresa SEGRETO, Salvatore CAPPABIANCA, Alfonso REGINELLI

Unit of Radiology, Department of Precision Medicine, Luigi Vanvitelli University of Campania, Naples, Italy


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BACKGROUND: Evaluating magnetic resonance imaging (MRI) in detecting, staging and follow-up new lesions in patients with Crohn’s disease (CD) in order to obtain a proper stratification of the population in study to achieve more accurate diagnostic and therapeutic paths.
METHODS: From 2015 to 2018, 103 patients diagnosed with CD aged between 19 and 72 years (mean age±46) were retrospectively studied. Enrolled patients have already been performed with two previous MRI exams.
RESULTS: 18.5% of all the patients had an history of surgery. Of these, 47.3% showed an improved state of disease only needing for follow-up, 31.5% showed postsurgical stenosis requiring for follow-up and/or pharmacological treatment also if disease was stable and the last 21% showed an active state of disease being considered as progressed patients. Instead, 81% of all the patients, only had history of a pharmacological treatment without any surgery and of these, 57% showed signs of an active-stage illness at MRI check-up. We could finally split this last population into three additional subgroups in relation to severity of disease activity, that was shown to be severe in 27% of all the cases, moderate in 66% mild in 7%.
CONCLUSIONS: MRI resulted to be a sensitive and non-invasive tool in detecting lesions for Crohn’s disease. It also shown to be crucial in the management of patients thanks to capability it offers in well orienting them, both in medical and in surgical treatment, obtaining a better overall outcome for the pathology.


KEY WORDS: Crohn disease; Inflammatory bowel diseases; Magnetic resonance imaging

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