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Journal of Radiological Review 2020 March-April;7(2):131-6

DOI: 10.23736/S2723-9284.20.00008-0


language: English

Evaluation of the relationship between dynamic magnetic resonance imaging findings and histopathological prognostic factors in breast cancer

Yeşim EROĞLU , Serpil AĞLAMIŞ, Adile F. DAĞLI

Department of Radiology, Fırat University School of Medicine, Elazıg, Turkey


BACKGROUND: The breast cancer is ranked among the most fatal kind of cancers. There are many histopathological prognostic factors in breast cancer which guide the treatment and help foresee the prognosis. In this study, the purpose is to determine whether there is a relationship between the dynamic MRI findings that are obtained before the operation of the patients with the diagnosis of breast cancer and the histopathological prognostic factors, and to have an opinion about the prognosis of the patients in this way.
METHODS: The study involved 65 patients aged between 35 and 68 who were histopathologically diagnosed with breast cancer and had a breast MRI before the operation. In addition to the morphological characteristics of the lesions, such as size and border features, functional characteristics such as contrasting patterns and time-signal intensity curves were evaluated from the obtained dynamic images. The classical histopathological prognostic factors such as the tumor diameter, the presence of axillary lymph nodes, the histological grade and the lymphovascular invasion as well as the ER, PR expressions were assessed as the Ki-67 and C-erb-B2 molecular histopathological prognostic factors.
RESULTS: In our study, a statistically significant relationship was found between the feature of spicule margin, which is one of the morphological findings of the dynamic breast MRI and the progesterone receptor positivity.
CONCLUSIONS: We believe that presence of spiculated borders in breast masses can be considered a marker of good prognosis, and that magnetic resonance imaging can be a good predictor of prognosis in breast cancer.

KEY WORDS: Breast neoplasms; Magnetic resonance imaging; Prognosis

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