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Il Giornale Italiano di Radiologia Medica 2019 Gennaio-Febbraio;6(1):16-24

DOI: 10.23736/S2283-8376.19.00156-6


language: English, Italian

Fetal magnetic resonance and post-natal magnetic resonance in the diagnosis of fetal anomalies of the central nervous system

Sara MEHRABI 1 , Enza GENCO 1, Mariacristina MATURI 1, Enrico BONINSEGNA 1, Francesca PRESTI 2, Riccardo MANFREDI 3, Giancarlo MANSUETO 1

1 Institute of Radiology, G.B. Rossi Polyclinic, University of Verona, Verona, Italy; 2 Department of Obstetrics and Gynecology, AOUI Verona, Verona, Italy; 3 Department of Diagnostic Imaging, Oncologic Radiotherapy, and Hematology, A. Gemelli University Hospital and Institute for Research and Care, Sacred Heart Catholic University, Rome, Italy


BACKGROUND: The aim of this study is to compare the accuracy of fetal magnetic resonance (FMR) with post-natal magnetic resonance (PNMR) in the diagnosis of fetal central nervous system (CNS) abnormalities.
METHODS: This retrospective study includes 50 patients sent from June 2010 to June 2017 to our Institute of Radiology at the G.B. Rossi Polyclinic in Verona after ultrasound diagnosis of malformations of the median line and/or malformations of the posterior cranial fossa, which were selected to perform FMR. Diagnoses of MRI were compared to diagnoses obtained after birth with PNMR in 15 live births. According to the PNMR results, the patients were divided into four groups: 1) same diagnosis between FMR and PNMR; 2) same diagnosis but different classification of the disease; 3) same diagnosis but further results to the PNMR; 4) different diagnosis.
RESULTS: FMR was performed at an average gestational age of 28 + 4 weeks (range 14-42) while PNMR at an average age of 3 months and 3 days (interval: 1 day to 5 months and 20 days). In the evaluation with PNMR were classified 9/15 patients (60%) as group A, 3/15 (20%) as group B, 2/15 children (13.3%) as group C and 1/15 children (6.7%) as group D.
CONCLUSIONS: FMR showed a high rate of accuracy in the pre- and post-natal diagnosis of CNS abnormalities.

KEY WORDS: Magnetic resonance imaging - Central nervous system diseases - Fetal development

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