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Il Giornale Italiano di Radiologia Medica 2018 Luglio-Agosto;5(4):550-4

DOI: 10.23736/S2283-8376.18.00102-X

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: Italian

Gastrointestinal neuroendocrine tumors: a case with periampullary duodenal localization

Ginevra DANTI, Monica M. LANZETTA, Gloria ADDEO, Diletta COZZI, Gianluca FREZZETTI, Antonella MASSERELLI, Silvia PRADELLA, Vittorio MIELE

SOD Radiodiagnostica di Emergenza Urgenza, Dipartimento dei Servizi, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italia


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Gastrointestinal neuroendocrine tumors (GI-NETs) are rare (1.2-1.5% of all gastrointestinal tumors). Neuroendocrine tumors (NETs) arise from the system of “APUD cells” (amine precursor uptake and decarboxylation). Two-thirds of NET arise in the mucosa of the GI tract, 25% in the lungs and the remaining 10% in other sites in the body. GI-NETs have traditionally been classified according to their embryologic site of origin: foregut (thymus, bronchus, gastric or duodenal mucosa, and pancreas), midgut (small bowel, appendix, and ascending colon) and hindgut (distal colon and rectum). The prevalence of these tumors at the level of Vater’s ampulla is unknown and extremely rare. Here, we report a case of GI-NETs with periampullary duodenal localization in a 87-year-old male patient who came to our observation for the appearance of jaundice, weight loss and increase in cholestasis indices.


KEY WORDS: Gastrointestinal neoplasms - Duodenum - Jaundice - Multidetector computed tomography

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