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Il Giornale Italiano di Radiologia Medica 2018 Maggio-Giugno;5(3):372-91

DOI: 10.23736/S2283-8376.18.00065-7


language: Italian

The role of imaging methods in the management of pediatric Hodgkin’s lymphoma: state of the art

Carmela BRILLANTINO 1 , Eugenio ROSSI 1, Salvatore BUFFARDI 2, Elio BIGNARDI 3, Michele COPPOLA 3, Rocco MINELLI 4, Raffaele ZECCOLINI 4, Massimo ZECCOLINI 5

1 Unità Semplice Dipartimentale di Radiologia ed Ecografia, Ospedale Pausilipon, AORN Santobono-Pausilipon, Napoli, Italia; 2 Dipartimento di Oncoematologia, Ospedale Pausilipon, AORN Santobono-Pausilipon, Napoli, Italia; 3 UOC Diagnostica per Immagini, Ospedale Cotugno, AORN dei Colli, Napoli, Italia; 4 Università degli Studi della Campania “Luigi Vanvitelli”, Napoli, Italia; 5 UOC Radiologia Ospedale Santobono, AORN Santobono-Pausilipon, Napoli, Italia


Hodgkin’s lymphoma in the 0-14 age group represents 6% of the tumors and 43% of all lymphomas; in the 15-19 age group it represents 23% of the tumors and 71% of all lymphomas. It is a systemic disease, therefore, all organs can be involved, including the central nervous system and the bones. In children at onset, lymph node and splenic involvement is more frequent and the clinical picture is different according to the sites where the disease is affected. Once the diagnosis is documented, the imaging methods currently used have a fundamental role in the staging phase. An accurate definition of the extension of the lymphoma to the diagnosis is of considerable importance for the prognosis, the choice of the most appropriate therapeutic treatment and for the evaluation of the response to the treatment. In particular, the identification of the disease in the initial stage may allow a milder therapy with fewer short-term and long-term side effects. The present review describes the role of the main imaging methods used in clinical practice in the management of the small patient with Hodgkin’s lymphoma.

KEY WORDS: Hodgkin lymphoma - Radiology - Diagnostic imaging - Tomography, X-ray computed - Positron emission tomography computed tomography

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