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Il Giornale Italiano di Radiologia Medica 2018 Marzo-Aprile;5(2):277-84

DOI: 10.23736/S2283-8376.18.00021-9

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: Italian

Atypical case of Kimura syndrome in a young woman without eosinophilia at diagnosis: the role of diagnostic imaging

Michele PIETRAGALLA 1 , Luigi BONASERA 2, Francesco MUNGAI 2, Andrea BIANCHI 1, Giovanni B. VERRONE 1, Diletta COZZI 1, Alba PIACENTI 1, Cosimo NARDI 1, Giuseppe CARACCHINI 3, Vittorio MIELE 2

Dipartimento di Scienze Biomediche Sperimentali e Cliniche Mario Serio, Istituto di Radiologia dell’Università, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italia; 2 Struttura Organizzativa Dipartimentale di Radiodiagnostica di Emergenza Urgenza, Dipartimento dei Servizi, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italia; 3 Struttura Organizzativa Dipartimentale di Radiologia Specialistica, Dipartimento dei Servizi, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italia


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Kimura syndrome (KS) is a rare, chronic inflammatory soft-tissue disorder which primarily affect head and neck region; its etiopathogenesis is unknown. This disorder has been primarily seen in young Asian males and it is characterized by a triad of signs and symptoms: painless subcutaneous masses in parotid and/or submandibular regions, blood and tissue eosinophilia and markedly elevated serum immunoglobulin E levels. KS can be easily mistaken with malignancies: differential diagnosis from odontogenic infections, sialadenitis, salivary glands neoplasms, lymphomas and parotid sarcoidosis is very tricky and based on clinical, laboratory and radiologic findings. Ultrasound-guided core biopsy is necessary for histopathological examination in order to confirm the diagnosis. We presented an unusual presentation of Kimura syndrome.


KEY WORDS: Angiolymphoid hyperplasia with eosinophilia - Hodgkin disease - Eosinophilia - Head and neck neoplasms - Lymphadenopathy - Immunoglobulin E

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