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Panminerva Medica 2019 December;61(4):457-63

DOI: 10.23736/S0031-0808.19.03639-5


language: English

PycnoRacer®, a fitness drink including Pycnogenol®, improves recovery and training in the Cooper test

Giulia VINCIGUERRA 1, Gianni BELCARO 2, 3, 4 , Beatrice FERAGALLI 2, 4, Maria Rosaria CESARONE 2, 3, Valentina ROTONDI 1, Andrea LEDDA 2, 3, Mariachiara ZUCCARINI 2, Morio HOSOI 2, 3, Mark DUGALL 2, 3, Marisa CACCHIO 4, Umberto CORNELLI 2, 3

1 Department of Medical and Oral Sciences, and Biotechnologies, University of L’Aquila, L’Aquila, Italy; 2 IRVINE3 Labs, Pescara, Italy; 3 International Agency for Pharma Standard Supplements (IAPPS), Pescara, Italy; 4 Department of Clinical, Oral, and Biotechnological Sciences, and Physiology, University of Chieti-Pescara, Pescara, Italy

BACKGROUND: This study evaluates the effects of training (on running distance measured with a Cooper test) in 3 weeks in non-professional athletes using PycnoRacer®, a fitness drink (FD) including Pycnogenol® during the training period.
METHODS: Pycnogenol® has been used in preclinical conditions and prevention. PycnoRacer® is a liquid combination of Pycnogenol® (15 mg), L-leucine (0.6 g), L-arginine (0.3 g), L-isoleucine (0.3 g), and L-valine (0.3 g). Two comparable groups (one using the FD) were formed: 60 training athletes were requested to drink one bottle 4 times/day, while 65 controls did not use PycnoRacer® or other comparable sports drinks. All subjects had a strong athletic background and advanced knowledge of the procedures of the tests. Two daily training sessions were completed. The sessions consisted in warming up and running a Cooper test.
RESULTS: 125 subjects completed the three weeks according to plans. There were nine dropouts due to logistical or working problems. Subjects using the FD improved on average by 18.83% (range 12-23%) in their running distance with training. The difference with controls was significant (P<0.05) at 3 weeks (controls improved on average by 8.9%; range 3-17.4%). The difference between the two groups was on average 9.93% (P<0.05). A comparable increase in VO2max was observed in the groups. In the FD group the increase was on average by 10.05 mL/kg/min compared to 4.95 mL/kg/min in controls, with a difference of 5.1 mL/kg/min (P<0.05). A VAS score showed comparable values. Lower values (concerning muscular pain and cramps) were observed in FD subjects (P<0.05) at the end of the 3 weeks of training. The level of plasma free radicals (PFR) values after the last Cooper test was significantly lower at 3 weeks in the FD group (P<0.05). No intolerance problem was observed by subjects using the FD.
CONCLUSIONS: In conclusion, the use of PycnoRacer® improved training, running distance, VO2max and PFR decreasing muscular pain and cramps.

KEY WORDS: Pycnogenols; Energy drinks; Athletic performanc

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