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Panminerva Medica 1999 December;41(4):351-4

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: English

Congenital hypopituitarism in a 48-year old adult. Natural course, hormonal study and MRI evidence

Pentimone F., Riccioni S., Del Corso L.

From the Department of Internal Medicine, Section of Geriatrics University of Pisa, Pisa, Italy


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A ­case of Congenital Hypopituitarism (CH) in an untreat­ed 48 yr-old-man is report­ed. The hor­mo­nal stud­ies dem­on­strat­ed a pan­hy­pop­i­tui­tar­ism and MR imag­ing ­revealed ­absence of pitui­tary ­stalk, ­small ante­ri­or pitui­tary rem­nant on the sel­la ­floor and ectop­ic neu­ro­hy­poph­y­sis at the ­tuber ciner­e­um. The pat­tern of hor­mo­nal respon­sive­ness sug­gests ­that CH encom­passes find­ings typ­i­cal of pri­mary ante­ri­or pitui­tary dis­ease and ­those of hypo­tha­lam­ic dys­func­tion.

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