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Otorinolaringologia 2001 September;51(3):125-9

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: Italian

Non-Hodgkin lymphoma of the piriform sinus: a case report and review of the literature

Saraniti C., Martines F., Caramanna C., Incandela S., Dispenza C.

Università degli Studi - Palermo Istituto di Clinica Otorinolaringoiatrica R


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Non-Hodgkin lymphoma has an extra-nodal origin in between 25 and 69.7% of cases depending on the series and the cervicofacial district is the second most frequent localisation in terms of incidence. In the “head-neck” region, the sites most frequently affected are: Waldeyer’s ring, nose, paranasal sinuses, salivary glands, thyroid, larynx and hypopharynx. The authors present a case of extranodal non-Hodgkin’s lymphoma of the piriform sinus and underline that the rarity of the localisation together with the often aspecific clinical objectivity of its onset, led to an understandable delay in diagnosis. Moreover, in this case the anamnesis suggested a phlogistic process resulting from an iatrogenic lesion of the piriform sinus during an endoscopic examination, which did not help identify the real nature of the pathology. Although the submucosal lesions do not raise the suspicion of a malignant process, the diagnosis is exclusively histological and a biopsy is therefore essential; for this reason, the ENT specialist must take these pathologies into consideration.

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