ORIGINAL ARTICLES   

Otorinolaringologia 2001 March;51(1):21-6

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: Italian

Use of monohydrate mometasone furoate acqueous nasal spray in the treatment of adenois syndromes preliminary study

Di Fortunato V., Carlevato M. T., Cravero L., Rosa S., Schenone G.

Ospedali Riuniti del Canavese - Ivrea (TO) UOA di Otorinolaringoiatria

Background. Advanced adenoid hypertrophy is known to be responsable for numerous morbid disorders. Over the past decade the number of surgical indications has gradually diminshed in favour of a greater use of pharmacological treatment. For this purpose, we evaluated the efficacy of topical steroid treatment in 30 paediatric patients (6-11 years): 17 males and 13 females due to undergo adenectomy.
Methods. Following recruitment and after the end of treatment patients underwent: anterior rhinoscopy, rhinofibroscopy (patients were selected with ≥60% obstruction of the choanal orifice); evaluation of expiratory flow using Glazer’s mirror; tympanometry. All patients were treated with monohydrate mometasone furoate aqueous nasal spray, after detersion of the nasal cavities using isotonic saline solution, for 3 months.
Results. The treatment was well tolerated by the young patients. There was an overall reduction of seromucous secretion in the nasal cavities and relatives assessed the symptoms to have improved in the majority of cases. The degree of obstruction was unchanged in 16 patients, slightly improved in 11 and significantly improved in 3 cases. This led to improved expiratory flow in 12/30 patients and indications for surgery were temporarily suspended in 3 patients. At the end of treatment 9/30 patients showed an improvement in the tympanometric curve.
Conclusions. The encouraging results obtained in this preliminary study prompt further larger-scale trials using this protocol, possibility associated with antibiotic treatment as an additional part of the study.