The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2021 Jan 26

DOI: 10.23736/S1824-4785.21.03333-1

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Update on diagnosis and treatment of hyperthyroidism. Ultrasonography and functional imaging

Simone A. SCHENKE ¹ ✉, Rainer GÖRGES ², Philipp SEIFERT ³, Michael ZIMNY ⁴, Michael C. KREISSL ¹

¹ Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany; ² Department of Nuclear Medicine, University Hospital Essen, Essen, Germany; ³ Clinic for Nuclear Medicine, University Hospital Jena, Jena, Germany; ⁴ Institute of Nuclear Medicine Hanau, Hanau, Germany

Both, ultrasonography but also radionuclide imaging using [99mTc]Pertechnetate or radioactive iodine isotopes are essential tools used during the diagnostic workup of hyperthyroidism with or without structural alterations of the thyroid. Colour duplex sonography and ultrasound elastography may add important information in order to find the cause of the hormone excess. During the last years, also hybrid imaging using SPECT/-(CT) or PET-based methods, such as [124]Iodine-PET/CT or [124]Iodine-PET/ultrasound also have nodularbeen increasingly used and especially play a role in the context of localizing ectopic thyroid tissue or in multinodular goiter. Recently also promising data has been published on the use of [99mTc]MIBI imaging in amiodarone induced hyperthyroidism.

KEY WORDS: Hyperthyroidism; Ultrasound; Graves‘ disease; Toxic nodule; Thyroid scan