REVIEW  UPDATE ON DIAGNOSIS AND TREATMENT OF HYPERTHYROIDISM Free access

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2021 June;65(2):102-12

DOI: 10.23736/S1824-4785.21.03333-1

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Update on diagnosis and treatment of hyperthyroidism: ultrasonography and functional imaging

Simone A. SCHENKE ¹ ✉, Rainer GÖRGES ², Philipp SEIFERT ³, Michael ZIMNY ⁴, Michael C. KREISSL ¹

¹ Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, University Hospital of Magdeburg, Magdeburg, Germany; ² Department of Nuclear Medicine, University Hospital Essen, Essen, Germany; ³ Clinic for Nuclear Medicine, University Hospital of Jena, Jena, Germany; ⁴ Institute of Nuclear Medicine Hanau, Hanau, Germany

Ultrasonography and radionuclide imaging using [^99mTc]Pertechnetate or radioactive iodine isotopes are essential tools used during the diagnostic workup of hyperthyroidism with or without structural alterations of the thyroid. Color duplex sonography and ultrasound elastography may add important information to find the cause of the hormone excess. During the last few years, hybrid imaging using SPECT/-(CT) or PET-based methods, such as [¹²⁴]Iodine-PET/CT or [¹²⁴]Iodine-PET/ultrasound have been increasingly used, playing a role in the context of localizing ectopic thyroid tissue or in multinodular goiter. Recently, promising data has been published on the use of [^99mTc]MIBI imaging in amiodarone induced hyperthyroidism.

KEY WORDS: Hyperthyroidism; Ultrasonography; Graves disease; Thyroid gland