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The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2018 September;62(3):321-4

DOI: 10.23736/S1824-4785.16.02868-X

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

Clinical value of quantitative measurements derived from GATED SPECT: motion and thickening, volumes and related LVEF

Walter NOORDZIJ 1 , Riemer H. SLART 1, 2

1 Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; 2 Department of Biomedical Photonic Imaging, University of Twente, Enschede, The Netherlands


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Radionuclide myocardial perfusion imaging using ECG-gated acquisition with single photon emission computed tomography (gated SPECT) is the current state of the art imaging modality for symptomatic patients with known or at least indeterminate likelihood of coronary artery disease. Gated SPECT provides a wide variety of additional information about left ventricular (LV) function measurements, for example LV volumes, ejection fraction (LVEF) and regional wall motion abnormalities. This contributes to a higher diagnostic accuracy, additional prognostic information and predicting benefit from revascularization in these patients. Gated SPECT is an easily reproducible and accurate tool, which provides additional information to myocardial perfusion, regarding functional LV data. Assessment of LV wall motion, volumes and LVEF increases diagnostic accuracy and has prognostic and predictive value for the individual patient.


KEY WORDS: Cardiac-gated single-photon emission computer-assisted tomography - Cardiac volume - Ventricular function, left

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