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REVIEWS IMAGING OF INFLAMMATION IN CARDIOVASCULAR DISEASE
The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2016 September;60(3):194-204
Copyright © 2016 EDIZIONI MINERVA MEDICA
language: English
New molecular probes of vascular inflammation
Alexis VRACHIMIS 1, 2, Lisa HONOLD 3, Andreas FAUST 3, 4, Sven HERMANN 3, 4, Michael SCHÄFERS 1-4 ✉
1 Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; 2 DFG CRC 656 “Molecular Cardiovascular Imaging”, Westfälische Wilhelms University Münster, Münster, Germany; 3 European Institute of Molecular Imaging, Westfälische Wilhelms University Münster, Münster, Germany; 4 DFG EXC 1003 “Cells in Motion” Cluster of Excellence, Westfälische Wilhelms University Münster, Münster, Germany
New molecular imaging approaches featuring the assessment of inflammatory processes in the vascular wall on top of existing anatomic and functional vessel imaging procedures could emerge as decisive tools for the understanding and prevention of cardiovascular events. In this respect imaging approaches addressing specific molecular and cellular targets in atherosclerosis are of high interest. This review summarizes the rationale and current status of nuclear imaging probes which possess high translational potential.