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Journal of Neurosurgical Sciences 2020 October;64(5):440-5

DOI: 10.23736/S0390-5616.17.04020-6


language: English

Impact of optic canal decompression on visual outcome in subtotal resected skull base meningiomas

Meike UNTEROBERDÖRSTER 1 , Oliver MÜLLER 1, Neriman ÖZKAN 1, Daniela PIERSCIANEK 1, Martin HADAMITZKY 2, Bernadette KLEIST 1, Ulrich SURE 1, Nicolai EL HINDY 1

1 Department of Neurosurgery, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany; 2 Institute of Medical Psychology and Behavioral Immunobiology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

BACKGROUND: Visual impairment (VI) due to neoplastic infiltration of the optic canal (OC) is frequently seen in skull base meningiomas representing a significant restriction in patients` quality of life. However, the delicate anatomy of this region often prevents gross total tumor resection. The aim of the present study was to evaluate the impact of intradural OC decompression and postoperative oncological procedure on preservation of visual acuity in subtotal resected skull base meningiomas.
METHODS: A retrospective analysis of 31 consecutive patients (19 females, 12 males; mean age 53 [range 18-78]), treated in our institution between 01/2011- 09/2014 was performed. Patients` charts were analyzed with special respect to operative procedure, postoperative treatment and procedural impact on late visual function.
RESULTS: Most patients (74.2%) had VI prior to surgery. A pterional craniotomy (97%) facilitated subtotal tumor removal in 71% of the patients with no intraoperative and a low rate (6.4%) of postoperative complications. Adjunctive radiotherapy was performed in 19.3% of the patients. Preoperative visual acuity was preserved or improved in 92% of the patients. Substantial tumor regrowth occurred in only 11.2% of the patients.
CONCLUSIONS: Intradural decompression of the OC stabilizes visual function in subtotally resected skull base meningiomas. Moreover, adjuvant radiotherapy seems to further benefit visual outcome which has to be evaluated in further prospective studies.

KEY WORDS: Optic nerve; Decompression; Skull base; Meningioma

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