CLINICAL CASES   

Journal of Neurosurgical Sciences 2006 March;50(1):9-12

Copyright © 2006 EDIZIONI MINERVA MEDICA

language: English

Extranodal marginal zone B-cell lymphoma most probably of MALT type appearing in CNS as parasagittal extracerebral tumor

Marinković M. ¹, Slavik E. ², Janković S. ³, čemerikic V. ³, Radulović D. ²

¹ Department of Experimental Oncology Institute of Oncology and Radiology of Serbia 2 Institute of Neurosurgery, Clinical Center of Serbia 3 Institute of Hematology, Clinical Center of Serbia

A 63 years old male patient with systemic extranodal marginal zone lymphoma, most probably originating from mucosa associated lymphoid tissue (MALT) involving central nervous system (CNS) is presented. The usual site of origin of this type of lymphoma was not identified. The diagnosis was stated after neurosurgery according to histopathology, immunohistochemistry and additional haematologic examination. Postoperative therapy included local irradiation (30Gy) of rest tumor, combined by Rituximab-CHOP (R-CHOP) protocol, which resulted in complete remission lasting three years up to now.