Home > Journals > Journal of Neurosurgical Sciences > Past Issues > Journal of Neurosurgical Sciences 2001 December;45(4) > Journal of Neurosurgical Sciences 2001 December;45(4):235-40

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

CASE REPORTS   

Journal of Neurosurgical Sciences 2001 December;45(4):235-40

Copyright © 2001 EDIZIONI MINERVA MEDICA

language: English

Primary leptomeningeal melanomatosis: early leptomeningeal enhancement on MRI

Celli P., Acqui M., Trillò G., Ramundo E. O., D’Andrea G., Roperto R., Ferrante L.

Department of Neurological Sciences, II Chair of Neurosurgery, University of Rome “La Sapienza”, Rome, Italy


PDF


One unusu­al ­case of pri­mary lep­tom­e­nin­geal melan­o­mat­o­sis is pre­sent­ed. The ­patient, 53-­year-old ­male, was admit­ted to our obser­va­tion for 1 ­month his­to­ry of psy­chas­the­nia and amne­sia. Despite sev­er­al poly­spe­cia­lis­tic clin­i­cal, neu­ro­ra­dio­log­i­cal and cyto­log­i­cal exam­ina­tions, con­clu­sive diag­no­sis was ­made ­only ­with a biop­sy of lep­tom­e­nin­geal nod­ule. The ­present ­case ­allows as to iden­ti­fy 2 stag­es in the evo­lu­tion of pri­mary dif­fuse lep­tom­e­nin­geal melan­o­mat­o­sis. The ­initial ­phase is char­ac­ter­ized by ­slight men­tal impair­ment with­out hydro­ceph­a­lus; dur­ing the lat­er ­phase ­there is ­severe, dif­fuse neu­ro­log­i­cal impair­ment and ­both CT and MRI ­show hyper­cap­ta­tion of the intra­cra­ni­al lep­to­me­ning­es and mul­ti­ple, lep­tom­e­nin­geal tumo­ral nod­ules.

top of page