Home > Journals > Minerva Urology and Nephrology > Past Issues > Articles online first > Minerva Urology and Nephrology 2021 Jun 22

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Publication history
Reprints
Permissions
Cite this article as
Share

 

 

Minerva Urology and Nephrology 2021 Jun 22

DOI: 10.23736/S2724-6051.21.04418-9

Copyright © 2021 EDIZIONI MINERVA MEDICA

The impact of Coronavirus Disease 2019 (COVID-19) on urinalysis parameters

Erhan DEMİRELLİ 1 , Mehmet G. SÖNMEZ 2, Doğan S. TOK 1, Sinan ÇETİN 3, Ercan ÖĞREDEN 1, Murat USTA 4, Safa AKYOL 1, Osman Ç. ÇİFTÇİ 1, Özay DEMİRAY 5, İlknur YAVUZ 6, Ural OĞUZ 1

1 Department of Urology, Faculty of Medicine, Giresun University, Giresun, Turkey; 2 Department of Urology, Faculty of Medicine, Necmettin Erbakan University Meram, Konya, Turkey; 3 Republic of Turkey, Ministry of Health Giresun Provincial Health Directorate Dr. Ali Menekşe Chest Diseases Hospital, Department of Infectious Diseases and Clinical Microbiology, Giresun, Turkey; 4 Department of Biochemistry, Giresun University Faculty of Medicine, Giresun, Turkey; 5 Republic of Turkey Ministry of Health Giresun Provincial Health Directorate Giresun University Prof. Dr. A. İlhan Özdemir Training and Research Hospital, Department of Urology, Giresun, Turkey; 6 Department of Clinical Microbiology and Infectious Diseases, Faculty of Medicine, Giresun University, Giresun, Turkey


PDF


BACKGROUND: Creatinine elevation and changes in urinalyse parameters may be seen due to acute kidney injury during COVID-19. In the present study, we aimed to investigate the changes in urinalysis of COVID-19 patients with normal kidney function.
METHODS: The data of COVID-19 patients with normal renal functions were retrospectively analyzed. Urinalysis parameters of these patients were recorded. The patients were divided into three groups as mild, moderate and severe with respect to the clinical course of the disease. It was examined whether the urine analysis values in the groups were different from normal reference values and whether these values were different between the groups. In addition, possible relationship between the urinalysis parameters and the clinical severity of the disease was investigated.
RESULTS: There are three groups; mild (n:40), moderate (n:38) and severe (n:42). Mean age were significantly higher in the severe group, while gender distribution of the groups was similar. (p=0.033) (p=0.091) Creatinine values of all patients were normal. There were 6.7% glucose positivity, 13.4% protein positivity, 5.8% urobilinogen positivity and 7.5% ketone positivity in urine dipstick analysis and these changes were all significantly higher than the reference values. (p=0.008, p<0.0001, p=0.016, p=0.016) Pyuria and hematuria were detected in 8.3% and 9.2%, respectively. The urinalysis parameters and urine microscopy findings were not affected by the severity of the disease.
CONCLUSIONS: Glycosuria, proteinuria, pyuria and hematuria may occur during COVID-19 disease, regardless of comorbidity and renal dysfunction. However, these urine parameters were not correlated with the severity of the disease.


KEY WORDS: COVID-19; Urinalysis; Hematuria; Pyuria; Kidney failure

top of page