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Minerva Urology and Nephrology 2021 October;73(5):668-71
DOI: 10.23736/S2724-6051.20.03615-2
Copyright © 2020 EDIZIONI MINERVA MEDICA
language: English
64CuCl2 PET/CT as a potential new imaging method in prostate cancer: illusion or reality?
Francesco CANTIELLO 1, Fabio CROCEROSSA 1 ✉, Giuseppe L. CASCINI 2, Giorgio I. RUSSO 3, Matteo FERRO 4, Sebastiano CIMINO 3, Giuseppe LUCARELLI 5, Rocco DAMIANO 1
1 Department of Urology, Magna Graecia University, Catanzaro, Italy; 2 Unit of Diagnostic Imaging and Nuclear Medicine, Magna Graecia University, Catanzaro, Italy; 3 Department of Urology, University of Catania, Catania, Italy; 4 Department of Urology, IRCCS European Institute of Oncology (IEO), Milan, Italy; 5 Department of Urology and Kidney Transplantation, University of Bari, Bari, Italy
Copper (Cu) is an essential element for many cellular functions, including proliferation and angiogenesis. High serum Cu levels have been demonstrated in patients with neoplasia as well as high intra-tumoral Cu levels have been reported. Preclinical and clinical evidences suggest its use, in the form of 64Copper chloride (64CuCl
KEY WORDS: Positron emission tomography computed tomography; Prostatic neoplasms; Nuclear medicine; Neoplasm staging; Radiotherapy