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Minerva Urologica e Nefrologica 2019 June;71(3):191-200

DOI: 10.23736/S0393-2249.19.03311-3


language: English

Bladder recurrence of primary upper tract urinary carcinoma following nephroureterectomy, and risk of upper urinary tract recurrence after ureteral stent positioning in patients with primary bladder cancer

Francesco A. MISTRETTA 1, 2 , Diego M. CARRION 2, 3, Sebastiano NAZZANI 4, Juan L. VÁSQUEZ 2, 5, 6, Cristian FIORI 7, Ottavio DE COBELLI 1, Francesco PORPIGLIA 7, Francesco ESPERTO 2, 8

1 Department of Urology, European Institute of Oncology, Milan, Italy; 2 European Society of Residents in Urology (ESRU), Brussels, Belgium; 3 Department of Urology, La Paz University Hospital, Madrid, Spain; 4 Department of Urology, IRCCS San Donato Policlinic, University of Milan, Milan, Italy; 5 Department of Urology, University Hospital of Zealand, Roskilde, Denmark; 6 Department of Urology, Copenhagen University Hospital, Herlev, Denmark; 7 Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy; 8 Department of Urology, Royal Hallamshire Hospital, Sheffield Teaching Hospital, Sheffield, UK

Upper tract urinary carcinoma (UTUC) and bladder cancer (BCa) share similar biological, histological and pathological characteristics. These resemblances could explain the high rate of synchronous and metachronous tumors affecting both upper urinary tract and bladder. In patients affected by primary UTUC bladder recurrence is quite common and it represents one of the major concerns during the follow-up of patients who underwent radical nephroureterectomy. Conversely, UTUC recurrence after primary non-muscular invasive BCa is a relatively rare event. Moreover, there is no clear evidence on whether the use of Double-J stenting as drainage in patients affected by BCa increases the risk of UTUC recurrence. The aim of the current study was to summarize the most recent evidence regarding the bladder recurrence after UTUC surgical treatment, and the UTUC recurrence after stent positioning in patients affected by primary BCa.

KEY WORDS: Urinary tract; Urinary bladder neoplasms; Urologic neoplasms; Nephroureterectomy; Stents

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