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A Journal on Nephrology and Urology

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Minerva Urologica e Nefrologica 2017 Dec 14

DOI: 10.23736/S0393-2249.17.03046-6


language: English

Selective clamping during laparoscopic partial nefrectomy: the use of near infrared fluorescence guidance

Francesco PORPIGLIA, Cristian FIORI, Enrico CHECCUCCI, Angela PECORARO, Michele DI DIO, Riccardo BERTOLO

Department of Urology, “San Luigi Gonzaga” Hospital, University of Turin, Orbassano, Turin, Italy


BACKGROUND: Near infrared fluorescence (NIRF) is being investigated as a helpful tool to enhance segmental arterial clamping in robotics. Available experiences with NIRF during standard laparoscopy are anecdotal. The aim of the study was to perform a single-center feasibility and results analysis of laparoscopic partial nephrectomy (LPN) performed using NIRF-guided selective clamping.
METHODS: May 2016-December 2016: 15 patients diagnosed with a renal mass suitable for nephron-sparing approach consecutively underwent LPN with NIRF-guidance technique. Demographic data, tumor characteristics; perioperative data; functional data; pathologic data; postoperative complications as classified according to the Clavien system were prospectively collected. Serum creatinine (SCr) and eGFR were assessed by serial measurements; 99mTc-MAG-3 nuclear renal scan was performed too. The measures were conducted preoperatively and at the 3rd postoperative month.
RESULTS: No complications were recorded. Use of NIRF guidance did not influence the safety of the procedure. Operative time wasn’t significantly increased with respect to the medians reported in the literature for LPN. Blood losses were negligible. NIRF-guidance allowed for successful selective clamping in 11 cases (73.3 %). In one case NIRF guidance allowed for the super-selective closing of the tumor-feeding artery. In 4 cases (26.7 %) selective ischemia was impossible and clamping of the main renal artery was chosen.
CONCLUSIONS: NIRF-guidance was successfully applied during laparoscopic PN, offering the surgeon additional information about kidney anatomy and perfusion. Our experience demonstrated the potential benefits of the new technology. The clinically relevance of selective clamping on functional outcomes is still a matter of debate.

KEY WORDS: Kidney - Laparoscopy - Partial nephrectomy - Renal ischemia - Image-guided surgery

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Publication History

Article first published online: December 14, 2017
Manuscript accepted: December 1, 2017
Manuscript revised: November 13, 2017
Manuscript received: September 1, 2017

Cite this article as

Porpiglia F, Fiori C, Checcucci E, Pecoraro A, Di Dio M, Bertolo R. Selective clamping during laparoscopic partial nefrectomy: the use of near infrared fluorescence guidance. Minerva Urol Nefrol 2017 Dec 14. DOI: 10.23736/S0393-2249.17.03046-6

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