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MINERVA UROLOGICA E NEFROLOGICA

A Journal on Nephrology and Urology


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Minerva Urologica e Nefrologica 2017 Nov 21

DOI: 10.23736/S0393-2249.17.03008-9

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Young Academic Urologist benign prostatic obstruction nomogram predicts clinical outcome in patients treated with transurethral resection of prostate: an Italian cohort study

Cosimo DE NUNZIO , Riccardo LOMBARDO, Antonio NACCHIA, Marianna DEROMA, Hassan ALKHATATBEH, Aldo BRASSETTI, Andrea TUBARO

Department of Urology, Ospedale Sant’Andrea, “Sapienza” University of Rome, Rome, Italy


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BACKROUND: Aim of our study was to test the Young Academic Urologist nomogram for the prediction of transurethral resection of prostate outcome in patients with lower urinary tract symptoms and benign prostatic enlargement.
METHODS: Between April 2014 and March 2016, a consecutive series of patients with lower urinary tract symptoms undergoing trans-urethral resection of prostate in one center were enrolled. At baseline patients were assessed with international prostate symptom score, prostate specific antigen, prostate volume, transitional zone volume, maximal urinary flow rate and post void residual urine. At 3 months after trans-urethral resection of prostate patients were evaluated with uroflowmetry and international prostate symptom score questionnaire. Maximum urinary flow and transitional zone volume were plotted on the Young Academic Urologist nomogram to predict trans-urethral resection of prostate outcome. Receiver-operator characteristics curve analysis was used to evaluate predictive properties of the nomogram for TURP outcome.
RESULTS: A total of 232 patients were consecutively enrolled. Out of them, 149 patients (65%) presented a positive outcome. The novel Young Academic Urologist nomogram presented an area under the curve of 0.77 (95%CI: 0.70- 0.83) for trans-urethral resection of prostate outcome prediction. At the best cut-off value of 75% (nomogram probability) the sensitivity was 62 % and specificity was 73%, the positive predictive value was 81% and the negative predictive value was 52%.
CONCLUSIONS: The Young Academic Urologist nomogram was, in our experience, an excellent tool to predict a positive outcome after transurethral resection of prostate, although further studies are needed to confirm our results.


KEY WORDS: Outcome - Lower urinary tract symptoms - Urodynamic - Non-invasive - Trans-urethral resection of prostate

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Publication History

Article first published online: November 21, 2017
Manuscript accepted: November 8, 2017
Manuscript revised: September 19, 2017
Manuscript received: July 13, 2017

Cite this article as

De Nunzio C, Lombardo R, Nacchia A, Deroma M, Alkhatatbeh H, Brassetti A, et al. Young Academic Urologist benign prostatic obstruction nomogram predicts clinical outcome in patients treated with transurethral resection of prostate: an Italian cohort study. Minerva Urol Nefrol 2017 Nov 21. DOI: 10.23736/S0393-2249.17.03008-9

Corresponding author e-mail

cosimodenunzio@virgilio.it