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MINERVA UROLOGICA E NEFROLOGICA

A Journal on Nephrology and Urology


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Minerva Urologica e Nefrologica 2017 December;69(6):548-55

DOI: 10.23736/S0393-2249.17.02828-4

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Clinical significance of intravesical prostatic protrusion in the management of benign prostatic enlargement: a systematic review and critical analysis of current evidence

Malte RIEKEN 1 , Fabrizio PRESICCE 2, Riccardo AUTORINO 3, Cosimo DE NUNZIO 2

1 Department of Urology, Medical University of Vienna, Vienna, Austria; 2 Department of Urology, Sant’Andrea Hospital, Sapienza University, Rome, Italy; 3 Department of Urology, Case Western Reserve University School of Medicine, Cleveland, OH, USA


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INTRODUCTION: Filling cystometry and pressure flow studies (PFS) are the most widespread used invasive urodynamic techniques in the assessment of male LUTS. However, these techniques are time- and cost-intensive. Intravesical prostatic protrusion (IPP) has been proposed as non-invasive method used to diagnose bladder outlet obstruction (BOO) in men with male lower urinary tract symptoms (LUTS). The purpose of the present review is to analyze the diagnostic and therapeutic relevance of IPP.
EVIDENCE ACQUISITION: A comprehensive systematic MEDLINE search was performed for English language reports published before June 2016 using the term “intravesical prostatic protrusion.”
EVIDENCE SYNTHESIS: We identified 28 eligible original articles. Determination of IPP seems as useful method to predict BOO. The area under the curve of IPP for the prediction of BOO was found to range from 0.708 (95% CI: 0.615-0.791) to 0.858 (95% CI: 0.809-0.908). IPP seems to have a predictive role in a successful trial without catheter following acute urinary retention. The percentage of successful TWOC in patients with IPP>10 mm was reported at 13% and 18%, respectively, compared to a approximately 80% chance of successful trial in patients with IPP<10 mm. The impact of IPP on postoperative outcomes following surgery for benign prostatic enlargement seems controversial. The heterogeneity of the current studies, the potential intra-observer variability and the potential learning curve need to be taken into account.
CONCLUSIONS: Analysis of IPP may be regarded as potential non-invasive alternative to standard PFS in the assessment of BOO. Patients with IPP>10 mm should be counseled regarding the high chance of need for surgical treatment following acute urinary retention.


KEY WORDS: Lower urinary tract symptoms - Prostatic hyperplasia - Transurethral resection of prostate

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Publication History

Issue published online: October 25, 2017
Article first published online: March 6, 2017
Manuscript accepted: February 23, 2017
Manuscript revised: February 6, 2017
Manuscript received: October 4, 2016

Cite this article as

Rieken M, Presicce F, Autorino R, De Nunzio C. Clinical significance of intravesical prostatic protrusion in the management of benign prostatic enlargement: a systematic review and critical analysis of current evidence. Minerva Urol Nefrol 2017;69:548-55. DOI: 10.23736/S0393-2249.17.02828-4

Corresponding author e-mail

m.rieken@outlook.com