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Minerva Chirurgica 2012 October;67(5):399-406


language: English

Multimodal approach to mild biliary pancreatitis based on a risk stratification of choledocholithiasis

Napolitano L., Antonopulos C., Waku M., Costantini R., D’Alessandro V., Risio D., Innocenti P.

Operative Unit of Surgical Pathologies, Department of Surgical Experimental Sciences, G. D’Annunzio University, “SS Annunziata” Hospital, Chieti, Italy


AIM: The management of acute mild biliary pancreatitis is multidisciplinary and still presents controversies in the diagnostic and therapeutic strategies. The aim of this retrospective study is to establish if a risk stratification of choledocholithiasis can optimize the employment of technological resources and medical competence in the treatment of individual patients in a tailored way. Our personal experience has then been compared with international literature. The main end-point was to evaluate the incidence of recurrence of acute pancreatitis. Secondary end point was to propose an affordable diagnostic and therapeutic algorithm for this relatively common disease.
METHODS: One hundred and one (101) patients affected by acute mild biliary pancreatitis were admitted in the Department of Patologia Chirurgica of “Ospedale SS. Annunziata” of Chieti from January 2004 to June 2011. Patients were divided in three groups; high (I), medium (II) and low risk (III) of choledocholithiasis (CBDS) according to clinical, laboratory and instrumental criteria. On the base of this division, patients in group I were subjected to ERCP with endoscopic sphinterotomy (ES) and subsequent laparoscopic cholecystectomy (LC). Group II patients underwent to MRCP, if positive for CBDS followed by ES and subsequently LC, if negative for CBDS directly LC. Group III patients underwent directly to LC associated with intra-operative cholangiography in selected cases.
RESULTS: No recurrence of acute pancreatitis was observed in patients who completed the diagnostic and therapeutic procedures.
CONCLUSION: We believe that the application of a patient stratification in risk groups for choledocholithiasis can optimize the use of medical and technological resources and helps to address a patient for a specific and more appropriate diagnostic and therapeutic investigation allowing, at the same time, to identify patients who can usefully undergo to a simplified diagnostic and therapeutic approach.

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